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Effects of topiramate on seizure susceptibility in kainate-kindled rats: Involvement of peripheral-type benzodiazepine receptors

✍ Scribed by Chunfu Chen; Senyang Lang; Gelin Xu; Xinfeng Liu; Pingping Zuo


Book ID
116880423
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
219 KB
Volume
17
Category
Article
ISSN
1059-1311

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Effects of chronic morphine pretreatment on the development of amygdaloid kindling, seizure suppression and benzodiazepine (BDZ) receptor binding in rats were evaluated. The morphine-pretreated animals showed faster acquisition of seizure activity. Further evaluation of the postictal seizure suppres