Effects of the umuDC, mucAB, and samAB operons on the mutational specificty of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis
β Scribed by Watanabe, Mie; Nohmi, Takehiko; Ohta, Toshihiro
- Book ID
- 122423871
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 754 KB
- Volume
- 314
- Category
- Article
- ISSN
- 0921-8777
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The antimutagenic effect of cinnamaldehyde on mutagenesis was investigated using ten kinds of chemical mutagen in Escherichia coli WP2s (uvr A-). In addition, the frequency of mutation induction by each mutagen in an SOS repair deficient (umuC-) strain was compared with that in a wild-type (umuC+) s
We have constructed double mutants carrying either ssb-1 or ssb-113 alleles, which encode temperature-sensitive single strand DNA binding proteins (SSB), and the uvrD::Tn5 allele causing deficiency in DNA helicase II, and have examined sensitivity to ultraviolet light (UV), recombination and spontan