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Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus

✍ Scribed by C. B. Sanjeevi; M. Landin-Olsson; I. Kockum; G. Dahlquist; Å. Lernmark


Book ID
115096498
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
427 KB
Volume
45
Category
Article
ISSN
0001-2815

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✍ Duncan Thomas; Janne Pitkäniemi; Bryan Langholz; Eva Tuomilehto-Wolf; Jaakko Tuo 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 755 KB

We fitted models for the main effects of alleles at the HLA-A, B, and DR loci and their haplotypes on the risk of insulin-dependent diabetes mellitus (IDDM). Empirical Bayes methods were used, assuming independent exchangeable normal priors for effects at each locus separately and for haplotype effe