## Abstract PTP–PEST is involved in the regulation of sealing ring formation in osteoclasts. In this article, we have shown a regulatory role for PTP–PEST on dephosphorylation of c‐Src at Y527 and phosphorylation at Y418 in the catalytic site. Activation of Src in osteoclasts by over‐expression of
✦ LIBER ✦
Effects of the protein tyrosine kinase inhibitor genistein and taurine on retinal function in isolated superfused retina
✍ Scribed by Matthias Lüke; Ralf Krott; Max Warga; Peter Szurman; Salvatore Grisanti; Karl Ulrich Bartz-Schmidt; Toni Schneider; Christoph Lüke
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 136 KB
- Volume
- 245
- Category
- Article
- ISSN
- 0065-6100
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Breast cancers frequently over-express a number of growth factor receptors. In addition, elevated src family kinase activity is present in a percentage of these neoplasms and has been implicated in signal transduction in these cells. Therefore, inhibiting tyrosine kinase activity is a potential appr