Effects of the porous structure of particles on selectivity in liquid chromatographic systems

✍ Scribed by Kowalczyk, J. S. ;Gazda, K. ;Herbut, G.

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 455 KB
• Volume: 2
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240021103

✦ Synopsis

Abstract

The effects produced in liquid‐solid chromatography by the heterogeneity of adsorbent particles on the behaviour of a number of substances were studied. As adsorbent silica gels were used which varied

In specific surface area and pore size,

In the diameter of particles of the same microporous structure.

A second series of experiments was conducted at various temperatures.

The dependences which were based on measurements of equivalent retention volumes were found to deviate somewhat from those theoretically predicted. However, they confirm and supplement some previous observations [l–5] according to which mass transport may be effected by only a portion of the packing particles if their porous structure is adequately heterogeneous. These observations are in contrast with views expressed by some authors [6, 7] who maintain that differences in mass transport resistance may only result in peak deformation.

It has also been demonstrated that the effects of the heterogeneity of particle structure in liquid chromatographic systems can be reduced by increasing the temperature.