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Effects of the phorbolester TPA and of the ionophore A 23187 on phospholipase A2and C activities in the mouse epidermal cell line HEL-30

✍ Scribed by G. Fürstenberger; M. Rogers; J. Faberman; M. Ganss; H. Richter; F. Marks


Book ID
112295075
Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
775 KB
Volume
113
Category
Article
ISSN
1432-1335

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The human undifferentiated histiocytic cell-line U937 can be induced to differentiate by incubation with 12-0-tetradecanoylphorbol-13-acetate (TPA) into macrophagelike cells. Dexamethasone reduced the prostaglandin production in TPA-differentiated U937 cells dose dependently, whereas undifferentiate