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Effects of the P2-purinoceptor antagonist, suramin, on human platelet aggregation induced by adenosine 5′-diphosphate

✍ Scribed by S.M.O. Hourani; D.A. Hall; C.J. Nieman


Book ID
117959712
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
929 KB
Volume
105
Category
Article
ISSN
0007-1188

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✍ Noel J. Cusack; Caroline J. Pettey 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 910 KB

Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P,,-purinoceptors. Both of these effects of ADP are inhibited competitively by ATP. Structure-activity relationships for phosphate-modified analogs of ADP and adenosine 5'-tri