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Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats

✍ Scribed by Han-Ting Zhang; Ying Huang; Neesha U. Suvarna; Chengjun Deng; Alicia M. Crissman; Allen T. Hopper; Michael De Vivo; Gregory M. Rose; James M. O’Donnell


Publisher
Springer
Year
2005
Tongue
English
Weight
192 KB
Volume
179
Category
Article
ISSN
0033-3158

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Nicotine and other nicotinic agonists have been found to improve performance in a variety of tasks, including the radial-arm maze to improve memory. There has been an active effort to develop novel nicotinic agonists for the treatment of cognitive dysfunction such as is seen in Alzheimer's disease.