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Effects of the novel cholinomimetic SDZ ENS 163 on scopolamine-induced cognitive impairment

โœ Scribed by N.R. Cutler; R. Polinsky; R.D. Seifert; J.J. Sramek; M. Moore; T.S. Wardle; D.C. Jones

Book ID
118856902
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
160 KB
Volume
35
Category
Article
ISSN
0006-3223

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โœ N. M. J. Rupniak; M. J. Steventon; M. J. Field; C. A. Jennings; S. D. Iversen ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 828 KB

The ability of four central cholinomimetics to reverse a scopolamine-induced spatial memory impairment or to improve visual recognition memory in primates was examined. Physostigmine (0.04-0.08 mg/kg IM) fully reversed the effects of scopolamine (0.03 mg/kg). Coadministration of pilocarpine (3.0-5.0