Pharmacokinetic study and effects on gro
✍
J. M. Kuhn; C. Basin; M. Mollard; B. Rougé; C. Baudoin; R. Obach; G. Tolis
📂
Article
📅
1993
🏛
Springer
🌐
English
⚖ 556 KB
We have studied the pharmacokinetics and the effects of BIM 23,014 (BIM), a new, long-acting octapeptide somatostatin analogue, on basal and stimulated GH secretion in normal men. BIM 250 micrograms sc significantly reduced a GHRH-induced increase in plasma GH. The continuous sc administration of BI