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Effects of the new calcium-agonists (±)-Bay W 5035 and (±)-Bay T 5006 in comparison to (−)-S-Bay K 8644 on haemodynamics in different in-vitro models

✍ Scribed by Rump, A.F.E.; Ratke, R.; Fricke, U.; Klaus, W.


Book ID
122837807
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
108 KB
Volume
8
Category
Article
ISSN
1532-8422

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Treatment of partially depolarised mouse diaphragm muscle in vitro with the Ca2(+)-channel agonist Bay K 8644 (1 microM) induces permeabilisation of the sarcolemma (visualised by penetration of procion yellow). Procion yellow staining was widespread (74% of fibres) after 2 h of treatment, but was ne