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Effects of the mutations Glu22 to Gln and Ala21 to Gly on zinc binding to the Aβ peptide

✍ Scribed by Walsh, D.M.; Clements, A.; Williams, C.H.; Allsop, D.

Book ID
124108011
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
167 KB
Volume
15
Category
Article
ISSN
0197-4580

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Circular dichroism and conformational an
Circular dichroism and conformational analysis of the membrane-modifying peptide -N-t-Boc-(Aib-L-Ala)5-Gly-Ala-Aib-Pro-Ala-Aib-Aib-Glu-(OBzl)-Gln-OMe with respect to alamethicin
✍ R. Oekonomopulos; G. Jung 📂 Article 📅 1980 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 665 KB

## Abstract The conformational analysis of the CD spectrum is reported for the synthetic and membrane‐modifying nonadecapeptide analog of alamethicin __N__‐__t__‐Boc‐(Aib‐L‐Ala)~5~‐Gly‐Ala‐Aib‐Pro‐Ala‐Aib‐Aib‐Glu(OBzl)‐ Gln‐OMe. The CD data are evaluated according to three different methods and are