Effects of the G(-656)A variant on CREB1 promoter activity in a glial cell line: Interactions with gonadal steroids and stress

Effects of the A(−115)G variant on CREB1

Effects of the A(−115)G variant on CREB1 promoter activity in two brain cell lines: Interactions with gonadal steroids

✍ George S. Zubenko; Hugh B. Hughes III 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 179 KB

## Abstract Major depressive disorder (MDD) is a leading contributor to disease burden worldwide. Previous genetic studies have revealed significant evidence of linkage of the __CREB1__ region to mood disorders among women from families with recurrent, early‐onset MDD (RE‐MDD), a severe and familia