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Effects of the endothelin receptor antagonist TAK-044 on hepatocyte element alterations in the ischemic-reperfused liver in Beagle dogs

โœ Scribed by Masamichi Imakita; Naoki Yamanaka; Nobukazu Kuroda; Yoshihiro Kitayama; Sadao Sasaki; Ikuko Nakagaki; Seiki Hori; Eizo Okamoto

Book ID
119135770
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
199 KB
Volume
28
Category
Article
ISSN
0168-8278

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Hepatoprotective effect of the endotheli
Hepatoprotective effect of the endothelin receptor antagonist TAK-044 against ischemia-reperfusion injury in the canine liver
โœ Y Kitayama; N Yamanaka; E Kawamura; N Kuroda; E Okamoto ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 423 KB ๐Ÿ‘ 1 views

The present study was designed to investigate if TAKparallel with a decrease in hepatic arterial and portal blood 044, a novel endothelin (ET) ET A /ET B receptor antagoflow. These pathological changes were reversed after ET-1 nist, inhibits ischemia-reperfusion liver injury. The iniinfusion was com