Effects of the combination of dl-α-difluoromethylornithine and diminazene aceturate in Trypanosoma congolense infection of dogs

Effects of DL-α-difluoromethylornithine

Effects of DL-α-difluoromethylornithine on the growth and metastasis of b16 melanoma in vivo

✍ Shunichiro Kubota; Nakaaki Ohsawa; Fumimaro Takaku 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 409 KB

The effects of DL-a-difluoromethylornithine (DFMO), a specific irreversible inhibitor of ornithine decarboxylase, on the growth of experimental mouse B 16-F 10 melanoma cells were investigated. DFMO (3%) in drinking water was administered to B16-FIO melanoma-bearing mice. A t 24 days, B16-FIO melano