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Effects of the Antiestrogenic Environmental Pollutant 3,3′,4,4′,5-Pentachlorobiphenyl (PCB #126) in Rat Bone and Uterus: Diverging Effects in Ovariectomized and Intact Animals

✍ Scribed by P.Monica Lind; E.F. Eriksen; L. Sahlin; M. Edlund; J. Örberg


Book ID
112266771
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
184 KB
Volume
154
Category
Article
ISSN
0041-008X

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✍ P.M Lind; S Larsson; H Oxlund; H Håkansson; K Nyberg; T Eklund; J Örberg 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 160 KB

The aim of this study was to compare effects of estrogen depletion (ovariectomy) and exposure to 3,3%,4,4%,5-pentachlorobiphenyl (PCB126) on bone strength and bone tissue composition in the rat. Half of the rats were ovariectomized (n=20) and the remainder were sham-operated. Ten of the ovariectomiz