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Effects of the 5-HT1Apartial agonists gepirone, ipsapirone and buspirone on local cerebral glucose utilization in the conscious rat

✍ Scribed by P. M. Grasby; T. Sharp; T. Allen; P. A. T. Kelly; D. G. Grahame-Smith

Publisher
Springer
Year
1992
Tongue
English
Weight
695 KB
Volume
106
Category
Article
ISSN
0033-3158

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The effects of a 5-HT1receptor ligand is
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✍ G. M. Goodwin; Rosemarie J. Souza; A. R. Green πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 557 KB

The effects of 2-(4-(4-(2-pyrimidinyl)-l-piperazinyl)-butyl)-1,2-benzoisothiazol-3(2H)one-1,1-dioxide hydrochloride (isapirone, TVX Q 7821), a putative 5-HT1 receptor antagonist, has been studied on various models of 5-HT receptor sub-type function. In mice TVX Q 7821 produced a dose-dependent inhib