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Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys

✍ Scribed by Tsuyoshi Ohmura; Motohiko Chachin; Sachiyo Tarui; Akihito Nagakura; Takashi Igarashi; Hironobu Ikeda; Kozaburo Ikegami; Hisato Kitagawa; Shuji Uchida

Book ID
114017394
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
242 KB
Volume
378
Category
Article
ISSN
0014-2999

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Effects of antihistamines, ebastine and terfenadine, on electrocardiogram in conscious dogs and cats
✍ Yoshihide Kii; Katsuyoshi Nakatsuji; Isamu Nose; Masafumi Yabuuchi; Michiaki Mat πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 146 KB

## Abstract The purpose of this study was to evaluate the effects of ebastine and terfenadine on the electrocardiogram of conscious dogs and cats. In dogs, terfenadine at oral doses of 30 mg/kg twice a day for 7 days prolonged the electrocardiographic QT interval and the corrected QT (QTc) interval