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Effects of temperature on ultraviolet-induced erythema of human skin

✍ Scribed by Christopher R. Shea; John A. Parrish


Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
409 KB
Volume
273-273
Category
Article
ISSN
0340-3696

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✦ Synopsis


Convective cooling of human skin to 20 ~ C or less for 1 h immediately after ultraviolet-B irradiation (UV-B, 290-320 nm) results in a significant increase in erythemal threshold when erythema was observed at 4-6h postirradiation. Cooling the skin immediately before UV-B irradiation showed no consistent influence on the erythema response. In neither case was an effect of cooling on erythemal threshold apparent when erythema was evaluated at 24 h postirradiation. These effects may be due to alterations in the diffusion kinetics of chemical mediators of inflammation, modification of vascular responsiveness, or reflect changes in temperature-dependent cellular repair or expression of UV-induced damage.


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