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Effects of temperature on adenosine A1 receptor activation in guinea pig hippocampus in vitro

✍ Scribed by Satoshi Fujii; Hiroshi Kato; Yoichiro Kuroda


Publisher
Springer
Year
2002
Tongue
English
Weight
97 KB
Volume
443
Category
Article
ISSN
0031-6768

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The effect of citalopram (CTP), a selective serotonin reuptake inhibitor antidepressant was studied on the rate and force of contractions of isolated guinea-pig atria. CTP (2-32 mg/ml) caused a dose-dependent decrease in the contractile force (7%-62%) and in the rate of contractions (11%-72%). These