Bioavailability of low (10 mg/kg) and high (50 mg/kg) doses of methylprednisolone was determined after oral administration of the free alcohol of methylprednisolone and iv administration of methylprednisolone sodium succinate. Plasma concentrations of methylprednisolone and methylprednisone (reversi
Effects of taraxacum mongolicum on the bioavailability and disposition of ciprofloxacin in rats
β Scribed by Min Zhu; Prudence Y. Wong; Ronald C. Li
- Book ID
- 109389197
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 67 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Sildenafil is the first oral therapeutic agent for the management of male erectile dysfunction. Its oral bioavailability is only 40% due to extensive presystemic elimination, mainly by CYP3A4. This study examined the effect of coadministration of ciprofloxacin or clarithromycin, which inhibit CYP3A4
The effects of ibuprofen on maternal phenytoin pharmacokinetics and fetal phenytoin acquisition were investigated in 19-day gestation Sprague-Dawley rats. A 5 mg kg-' bolus injection of I4C-phenytoin was given with and without (control) pretreatment with 12.5 mg kg-' of ibuprofen. Maternal plasma an