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Effects of tamoxifen on telomerase activity in breast carcinoma cell lines

โœ Scribed by Wade K. Aldous; Amber J. Marean; Mary J. DeHart; Louis A. Matej; Katherine H. Moore

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
178 KB
Volume
85
Category
Article
ISSN
0008-543X

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โœฆ Synopsis

The authors tested the effects of the antiestrogenic agent tamoxifen on telomerase activity and cell proliferation in MCF-7 and MDA-MB-231 breast carcinoma cell lines. MCF-7 cells belong to a known estrogen receptor positive cell line, whereas MDA-MB-231 cells, previously thought to be estrogen receptor negative, are now shown to contain estrogen receptor-โค.

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