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Effects of tamoxifen on serotonin transporter and 5-hydroxytryptamine2A receptor binding sites and mRNA levels in the brain of ovariectomized rats with or without acute estradiol replacement

✍ Scribed by Barbara E.H Sumner; Kay E Grant; Roberta Rosie; Ch Hegele-Hartung; K.-H Fritzemeier; George Fink


Book ID
117387405
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
206 KB
Volume
73
Category
Article
ISSN
0169-328X

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Acute 17␀-estradiol treatment had been shown to downregulate the 5-HT 1A receptor mRNA expression in limbic areas of the female rat brain. The aim of the present study was to determine the effects of chronic 17␀-estradiol treatment on 5-HT 1A receptor mRNA expression and 5-HT 1A receptor binding in