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Effects of systemic administration of lidocaine and QX-314 on hyperexcitability of spinal dorsal horn neurons after incision in the rat

โœ Scribed by Mikito Kawamata; Shigekazu Sugino; Eichi Narimatsu; Masanori Yamauchi; Tomohiro Kiya; Shingo Furuse; Akiyoshi Namiki

Book ID
116817853
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
502 KB
Volume
122
Category
Article
ISSN
0304-3959

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Systemic tocainide relieves mechanical hypersensitivity and normalizes the responses of hyperexcitable dorsal horn wide-dynamic-range neurons after transient spinal cord ischemia in rats
โœ J -X. Hao; Y -X. Yu; ร…. Seiger; Z. Wiesenfeld-Hallin ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 667 KB

In the present study we examined the effect of systemic tocainide on sensory hypersensitivity in rats after spinal cord ischemia induced by a photochemical technique. After induction of spinal cord ischemia the rats exhibited a sensory disturbance which was mainly expressed as vocalization to innocu