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Effects of sulfonylurea drugs on adiponectin production from 3T3-L1 adipocytes: Implication of different mechanism from pioglitazone

✍ Scribed by Yukiko Kanda; Masafumi Matsuda; Kazuhito Tawaramoto; Fumiko Kawasaki; Mitsuru Hashiramoto; Michihiro Matsuki; Kohei Kaku

Book ID
116406167
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
399 KB
Volume
81
Category
Article
ISSN
0168-8227

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✍ Takahide Ikeda; Kazuo Kajita; Wu Zhiliang; Takayuki Hanamoto; Ichiro Mori; Kei F πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 326 KB

## Abstract PPARΞ³ plays a key role in adipocyte specific gene expression. In this study, we assessed the effects of phorbol ester (TPA)‐sensitive PKC (c/nPKC) activation on the expression of adipocyte specific genes and inflammation related genes. Treatment with both TPA and TNFΞ± decreased mRNA lev