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Effects of substituents on the rates of deacylation of substituted benzoyl papains. Role of a carboxylate residue in the catalytic mechanism

✍ Scribed by Zannis, Vassilios I.; Kirsch, Jack F.


Book ID
127247952
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
726 KB
Volume
17
Category
Article
ISSN
0006-2960

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## Abstract In alcohols and esters, a neighbouring dialkylamino group can enhance the reactivity towards acylation and deacylation, respectively, that is, such amino alcohols can act as transacylation catalysts like DMAP. This effect is dependent on the number of (carbon) spacer atoms, flexibility