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Effects of SR 141716A after acute or chronic cannabinoid administration in dogs

✍ Scribed by Aron H. Lichtman; Jenny L. Wiley; Kari L. LaVecchia; Scott T. Neviaser; David B. Arthur; David M. Wilson; Billy R. Martin

Book ID
114016561
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
126 KB
Volume
357
Category
Article
ISSN
0014-2999

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To characterize the behavioral and biochemical effects of the cannabinoid CB1 antagonist SR141716A, we injected the compound intraperitoneally (ip) at doses from 0.625 mg/kg to 5 mg/kg in rats. SR141716A per se induced a dose-dependent increase of some behavioral signs such as wet dog and head shake