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Effects of somatostatin analogue SMS 201–995

✍ Scribed by G. J. Poston; J. Gillespie; D. M. Nott; J. N. Baxter; T. G. Cooke; S. A. Jenkins

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
296 KB
Volume
77
Category
Article
ISSN
0007-1323

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Somatostatin inhibits exocrine pancreatic and has been used for treatment of pancreatic f i ~t u l a ~-~. The short ti, < 3 m i n in man6, and the risk of a rebound effect when treatment is interrupted7, require the peptide to be continuously infused intravenously. This may be circumvented by using

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Somatostatin analogue SMS 201–995 (octreotide) as a possible solution to the dumping syndrome after gastrectomy or vagotomy
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Abstract The dumping syndrome, which may follow partial gastrectomy or truncal vagotomy and drainage, may be refractory to treatment. The aim of this study was to determine the effect of the somatostatin analogue. SMS 201-995 (octreotide), on dumping provoked by hypertonic glucose. Ten patients with