Morphine effects on human REM state, wak
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David C. Kay; Richard B. Eisenstein; Donald R. Jasinski
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Article
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1969
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Springer
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English
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After 4 adaptation nights, IM doses of morphine sulfate (7.5, 15, 30 rag/70 kg) and placebo were studied in 8 male postaddicts, using a cross-over design with randomized block analysis to demonstrate significant drug effect. Morphine decreased the number and duration of REM periods, delayed the onse