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Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers

✍ Scribed by Hiroyuki Kamei; Ami Isaji; Yukihiro Noda; Kazuhiro Ishikawa; Koji Senzaki; Kiyofumi Yamada; Kazumitsu Sugiura; Yasushi Tomita; Toshitaka Nabeshima


Book ID
113039635
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
500 KB
Volume
304
Category
Article
ISSN
0340-3696

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## Abstract Since most classical (first‐generation) antihistamines have undesirable sedative effects on the central nervous system (CNS), newer (second‐generation) antihistamines have been developed to relieve the sedative effects and to improve the patient's quality of life. However, the psychomot