The effects of diazepam on learning and memory were investigated in a double-blind study of 28 Uruguayan university women who were randomly assigned to four treatments, seven subjects each: placebo, 0.1, 0.2, and 0.3 mg/kg diazepam orally. Subjects were presented with five uncategorized and categori
Effects of single oral doses of clobazam, diazepam and lorazepam on performance tasks and memory
β Scribed by A. Patat; M. J. Klein; M. Hucher
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 678 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
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## Abstract This was a doubleβblind, placeboβcontrolled crossover study in 15 healthy female volunteers. It consisted of five sessions, separated by 1 week washβout between sessions. The purpose of the trial was to study the potential amnesic and sedative activity of clobazam and lorazepam, and the
Twelve healthy participants received double-blind single doses of lorazepam 1 mg, 2 mg and placebo at weekly intervals using a Latin square design. Prior to administration and 2 h afterwards, a battery of tests was used to assess psychomotor and cognitive function and to elicit event-related potenti