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Effects of single and continuous administration of amyloid β-peptide (25–35) on adenylyl cyclase activity and the somatostatinergic system in the rat frontal and parietal cortex

✍ Scribed by A. Hervás-Aguilar; L. Puebla-Jiménez; E. Burgos-Ramos; D. Aguado-Llera; E. Arilla-Ferreiro

Book ID
116786957
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
333 KB
Volume
135
Category
Article
ISSN
0306-4522

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✍ E. Burgos-Ramos; A. Hervás-Aguilar; L. Puebla-Jiménez; M.C. Boyano-Adánez; E. Ar 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB 👁 1 views

## Abstract Although alterations in adenylate cyclase (AC) activity and somatostatin (SRIF) receptor density have been reported in Alzheimer's disease, the effects of amyloid β‐peptide (Aβ) on these parameters in the hippocampus are unknown. Our aim was to investigate whether the peptide fragment A