Effects of sex hormones and of pregnancy on the selenium metabolism

✍ Scribed by Dietrich Behne; Walter Elger; Wolfgang-Schmelzer; Michael Witte

• Publisher: Elsevier Science
• Year: 1976
• Weight: 195 KB
• Volume: 5
• Category: Article
• ISSN: 0006-3061
• DOI: 10.1016/s0006-3061(00)82017-7

✦ Synopsis

In order to obtain information about;:the hormonal regulation of the selenium metabolism. the element level in the blood serum of rats was determined by means of neutron activation analysis after administration of sex hormones and during pregz nancy. WhiIe the decreases in the mean seienium concentrations found after the treatment with progesterone and progesterone + estrone were too low to enable us to establish response patterns, marked changes were observed in the serum of gravid rats. Here the selenium level dropped significantly (P < 0.001) by 25% between the 10th and 15th day of gestation.