✦ LIBER ✦

Effects of sequence alignment procedures on estimates of phylogeny

✍ Scribed by Nick Goldman

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 49 KB
Volume: 20
Category: Article
ISSN: 0265-9247
DOI: 10.1002/(sici)1521-1878(199804)20:4<287::aid-bies4>3.0.co;2-n

No coin nor oath required. For personal study only.

✦ Synopsis

Previous debate about statistical variation in inferred phylogenies has focused on procedures for the estimation of evolutionary relationships from aligned sequences. Morrison and Ellis 1 have recently drawn attention to additional variation attributable to the alignment procedure used and have suggested that this may be highly significant. This raises doubts about our ability to infer reliable phylogenies. Although concerns may not be as serious as their analyses at first imply, Morrison and Ellis 1 have performed a useful service in reminding us that accurate sequence alignment is a crucial part of molecular phylogenetics.

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