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Effects of selective tachykinin receptor antagonists on capsaicin- and tachykinin-induced bronchospasm in anaesthetized guinea-pigs

✍ Scribed by Lido Ballati; Stefano Evangelista; Carlo Alberto Maggi; Stefano Manzini

Book ID
115887448
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
575 KB
Volume
214
Category
Article
ISSN
0014-2999

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Use of Selective Agonists and Antagonist
Use of Selective Agonists and Antagonists to Characterize Tachykinin Receptors Mediating Airway Responsiveness in Anaesthetized Guinea-pigs
✍ L. Yuan; E. Burcher; B.S. Nail πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier 🌐 English βš– 426 KB

SUMMARY: Tachykinins are potent bronchoconstrictors. Here we have used novel highly selective agonists and antagonists to characterize tachykinin receptors mediating bronchoconstriction and hypotension in anaesthetized, paralysed guinea-pigs. Total lung resistance \(\left(R_{L}\right)\) and dynamic