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Effects of S(+)-efonidipine on the rabbit sinus node action potential and calcium channel subunits CaV1.2, CaV1.3 and CaV3.1

✍ Scribed by Hikaru Tanaka; Iyuki Namekata; Toru Ogawa; Yayoi Tsuneoka; Chisa Komikado; Akira Takahara; Naoko Iida-Tanaka; Hiroko Izumi-Nakaseko; Hiromichi Tsuru; Satomi Adachi-Akahane

Book ID
113588972
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
377 KB
Volume
649
Category
Article
ISSN
0014-2999

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## Abstract Low‐voltage‐activated (LVA) Ca^2+^ channels play a critical role in the generation of burst firing in the thalamus. Recently, three LVA Ca^2+^ channel isoforms (Ca~v~3.1, Ca~v~3.2, Ca~v~3.3) have been identified in the reticular thalamic nucleus (RE). Previous electrophysiological and m