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Effects of S-adenosyl-L-methionine (SAMe) therapy in cholestatic acute viral hepatitis in alcoholics

✍ Scribed by Tatiana Tcherveniakova; Georgi Popov; Penka Ilieva


Book ID
118565809
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
112 KB
Volume
36
Category
Article
ISSN
0168-8278

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In this study, ethinylestradiol inhibited the uptake of taurocholate by cultured rat hepatocytes, increasing the Krn while leaving the Vmax unchanged. S-Adenosyl-L-methionine (SAMe) had no effect on taurocholate uptake or release, but was able to reverse the competitive inhibition induced by ethinyl

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