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Effects of ready to drink teas on AhR- and PXR-mediated expression of cytochromes P450 CYP1A1 and CYP3A4 in human cancer cell lines and primary human hepatocytes

✍ Scribed by Alzbeta Kamenickova; Radim Vrzal; Zdenek Dvorak

Book ID: 113626231
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 544 KB
Volume: 131
Category: Article
ISSN: 0308-8146
DOI: 10.1016/j.foodchem.2011.09.104

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## Abstract Four β‐glycosides of flavonoligan silybin, i.e. silybin β‐galactoside, silybin β‐glucoside, silybin β‐maltoside, silybin β‐lactoside were synthesized in order to improve silybin water solubility and bioavailability (Křen et al., J Chem Soc, Perkin Trans 1, 2467–2474, 1997). The presente