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Effects of pyrethroids on the activity of a purified (Ca2+-Mg2+)-ATPase

โœ Scribed by O.T. Jones; A.G. Lee


Book ID
119027485
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
860 KB
Volume
25
Category
Article
ISSN
0048-3575

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The purified Ca2+/Mg2+ ATPase from rat heart plasma membrane was activated by Ca2+ and Mg2+ with Ka values of 1.47 mM and 2.51 mM, respectively; other divalent cations also activated the enzyme but to a lesser extent. Divalent cations like Cu2+, Zn2+, Ni2+, Cd2+ were potent inhibitors of the enzyme