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Effects of pulsed electromagnetic fields on the foreign body response to particulate debris in a rabbit model

✍ Scribed by T. DoVan; M. C. Zimmerman; P. Bednarz; N. Alexander; M. Deehan

Publisher: Wiley (John Wiley & Sons)
Year: 1993
Tongue: English
Weight: 864 KB
Volume: 4
Category: Article
ISSN: 1045-4861
DOI: 10.1002/jab.770040203

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✦ Synopsis

The effect of pulsed electromagnetic fields (PEMFs) on the foreign body response to particulate debris, similar in morphology and quantity to wear debris present in the tissues around loose total joint prostheses, was investigated using a rabbit model. Cobalt chrome pins were inserted into the femurs along with particulate debris consisting of ultra high molecular weight polyethylene (UHMWPE), polymethylmethacrylate (PMMA), and cobalt chrome (CC). The particles induced a significant cellular response compared to the control animals that did not receive any debris. The application of PEMFs did not increase this foreign body response, nor did it have an effect on the number of resorption cavities, cortical area, or cortical thickness.

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