The stability of p21 WAF1 and p53 is increased by UV radiation or proteasome inhibitors in normal and some tumor cells. However, p21 WAF1 can either stimulate in vitro assembly of active cyclin-kinase complexes at low concentrations or inhibit this activity at high concentrations. Also, ectopic p21
Effects of protein kinase inhibitors on radiation-induced WAF1 accumulation in human cultured melanoma cells
β Scribed by Fujino; Ohnishi; Asahi; Wang; Takahashi; Ohnishi
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 246 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0007-0963
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