The activation of intracellular contractile proteins induces vascular contraction mediated through signal transduction mechanisms. Protein kinase C (PKC) is involved in this signal transduction. The purpose of the present study was designed to investigate the role of PKC on EtOH-, KCl-and phorbol 12
โฆ LIBER โฆ
Effects of protein kinase C activation on norepinephrine-induced phosphatidylinositide hydrolysis in intact rat aorta
โ Scribed by Eulalia Bazan; Anita K. Campbell; Robert M. Rapoport
- Book ID
- 113398546
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 465 KB
- Volume
- 245
- Category
- Article
- ISSN
- 0922-4106
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Protein kinase C (PKC) modulates the activity and phosphorylation of the catalytic alpha-subunit of sodium-potassium-adenosine triphosphatase (Na+/K+ ATPase) in normal arteries. Because PKC is altered in cirrhotic aortae, Na+/K+ ATPase may also be altered in these arteries. The aim of the present st