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Effects of protease inhibitiors on adenylate cyclase activation and aldosterone production in rat adrenal zona glomerulosa cells

โœ Scribed by M. E. McAuley; P. W. Raven; G. P. Vinson


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
419 KB
Volume
3
Category
Article
ISSN
0263-6484

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Acute effects and action mechanisms of prolactin (PRL) on aldosterone secretion in zona glomerulosa (ZG) cells were investigated in ovariectomized rats. Administration of ovine PRL (oPRL) increased aldosterone secretion in a dose-dependent manner. Incubation of [3H]-pregnenolone combined with oPRL i