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Effects of polyethylene glycol on stability of α-chymotrypsin in aqueous ethanol solvent

✍ Scribed by L.M Simon; M Kotormán; A Szabó; G Garab; I Laczkó


Book ID
116288203
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
661 KB
Volume
317
Category
Article
ISSN
0006-291X

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The effectiveness of the covalent modification of a-chymotrypsin with methoxy poly(ethylene glycol) (PEG) to afford its stabilization during encapsulation in poly(lactic-co-glycolic) acid (PLGA) microspheres by a solid-in-oil-in-water method was investigated. a-Chymotrypsin was chemically modified w