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Effects of Polychlorinated Biphenyls (PCBs) on Brain Tyrosine Hydroxylase Activity and Dopamine Synthesis in Rats

✍ Scribed by Neepa Y. Choksi; Prasada Rao S. Kodavanti; Hugh A. Tilson; Raymond G. Booth

Book ID
115608820
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
98 KB
Volume
39
Category
Article
ISSN
0272-0590

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## Abstract Sixty percent of the dopamine β‐hydroxylase (DBH) (EC 1.14.2.1) activity in rat brain was found to be bound to membrane fractions. The additions of Triton X‐100 solubilized DBH completely and permitted the estimated of the total enzyme activity. In homogenates the DBH could be detected