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Effects of POH in combination with STI571 on the proliferation and apoptosis of K562 cells

✍ Scribed by Chen Yan; Hu Dong

Publisher
Springer-Verlag
Year
2004
Tongue
Chinese
Weight
406 KB
Volume
24
Category
Article
ISSN
0510-9752

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## Abstract ## BACKGROUND Chronic myelogenous leukemia (CML) is characterized by a molecular aberration, a fusion __BCR‐ABL__ gene encoding for aberrant tyrosine kinase activity, which is crucial in the pathogenesis of CML. In vitro, inhibition of BCR‐ABL protein tyrosine kinase activity by a tyro