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Effects of plasminogen activator inhibitor-1 on ischemic brain injury in permanent and thrombotic middle cerebral artery occlusion models in mice

✍ Scribed by N. NAGAI; Y. SUZUKI; B. VAN HOEF; H. R. LIJNEN; D. COLLEN


Book ID
109149110
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
200 KB
Volume
3
Category
Article
ISSN
1538-7933

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## Abstract The lipid mediator prostaglandin E~2~ (PGE~2~) exhibits diverse biologic activity in a variety of tissues. Four PGE~2~ receptor subtypes (EP1–4) are involved in various physiologic and pathophysiologic conditions, but differ in tissue distribution, ligand‐binding affinity, and coupling