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Effects of phosphonoacetic acid on subacute myeloopticoneuropathy virus in vitro and in vivo

✍ Scribed by Y. Nishibe; Y. K. Inoue

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
274 KB
Volume
2
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

The effect of phosphonoacetic acid (PAA) in vitro and in vivo on subacute myeloopticoneuropathy (SMON) virus isolated from the spinal fluid of SMON patients was studied. PAA inhibited multiplication of SMON virus in cultures, but it did not show a direct effect on the virus. The drug did not influence the disease when the medication was started from 10 days after infection of suckling mice. However, the drug did elicit a delay in the incubation period.

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