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Effects of phorbol ester and cholecystokinin on the intracellular distribution of protein kinase C in rabbit pancreatic acini

โœ Scribed by Antoine G. H. EDERVEEN; Sjenet E. VAN EMST-DE VRIES; Jan Joep H. H. M. DE PONT; Peter H. G. M. WILLEMS

Book ID
115128390
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
635 KB
Volume
195
Category
Article
ISSN
1432-1327

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๐Ÿ“œ SIMILAR VOLUMES

Cellular distribution of gastric chief c
Cellular distribution of gastric chief cell protein kinase C activity: Differential effects of diacylglycerol, phorbol esters, carbachol, and cholecystokinin
โœ Robert D. Raffaniello; Jean-Piean Raufman ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 649 KB

## Abstract Stimulation of chief cells with carbachol or cholecystokinin (CCK) results in the production of inositol trisphosphate (IP~3~) and diacylglycerol (DAG). Although IP~3~ increases cell calcium concentration, thereby stimulating pepsinogen secretion, the role of DAG and its target, protein