The effects of external divalent cations on the steady-state open probability (Po), opening and closing rates, and conductance ofbatrachotoxin (BTX)-activated Na channels were studied in planar lipid bilayers. External divalent cations shifted the midpoint of the Po versus membrane potential (Vm) re
Effects of Permeant Cations on K+Channel Gating in Nerve Axons Revisited
β Scribed by J.R. Clay
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 186 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0022-2631
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The effects of different intracellular divalent cations on the gating of single batrachotoxin-activated Na Β§ channels were investigated in planar lipid bilayers. Intracellular divalent cations increased the open probability (Po) of Na + channels; the gating curve [Po versus membrane potential (Vm) r
Using the previously reported ab initio interaction energies among K ' , Na+, water, and Gramicidin A (GA), this report presents Monte Carlo simulations for the microscopic effect of an applied voltage (0.5 V/32 A) on a solvated gramicidin. The reorientation of water molecules due to the applied vol